Amol G. Dikundwar

Establishing Antidiabetic Potential of Navayasa Churnam: Phyto-Metabolomics, Systems Pharmacology, In Vitro, In Vivo, and In Silico Studies

Intranasal Delivery of Piceatannol-Loaded Liposomes for Glioblastoma Management: Formulation Optimization, In Vitro, Ex Vivo, In Ovo and LC-MS/MS- Based In Vivo Pharmacokinetic and Brain Distribution Assessment

Overall, this research establishes PIC-LPO as a safe, non-invasive, and effective strategy to enhance brain delivery and antiangiogenic therapy, highlighting the translational potential of PIC for GBM management.

Rational Coformer Screening of Multicomponent Crystals of Abiraterone Acetate Using Machine Learning (ML) and Multicomponent Hydrogen Bond Propensity (MCHBP): A Comprehensive Structural and Computational Investigation

A novel predictive framework that combines machine learning with molecular complementarity hydrogen-bond propensity (MCHBP) for efficient screening of coformers for efficient screening of coformers is developed.

Intranasal Pacritinib-loaded nanoemulsion for Glioblastoma management: In Vitro, ex Vivo, 3D spheroid and In vivo brain biodistribution studies.

It can be concluded that PAC-NE is a non-invasive delivery system which shows promising results for better brain delivery thereby supporting the clinical translation of PAC for GBM therapy.

Novel salicylamido sulfonamides as CD73 immune checkpoint inhibitors: Synthesis and in vitro biological evaluation.

In silico ADME analysis indicated that both lead compounds possess favourable drug-like properties, with no Lipinski's rule-of-five violations, balanced lipophilicity, and acceptable predicted oral absorption, supporting their pharmacokinetic potential.