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An-Yi Tang

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#gene editing Open access Sep 2026

Multi-layer Cis-molQTLs Reveal Regulatory Architecture and Enhance Heritability Explanation for Complex Traits in Cattle.

Genome-wide association study (GWAS) analyses have identified numerous loci associated with economic traits in cattle. Many of these loci reside in noncoding regions, and the regulatory mechanisms through which they influence complex traits remain poorly understood. Here, we integrated 657 RNA-seq libraries from 275 Hu...

Shiyuan Qiu, Li-Li Du, Bo-Yu Zhang et al. · 0 citations
Open access Jul 2026

Integrating bulk and single-cell RNA sequencing with GWAS reveals regulatory networks underpinning complex traits in beef cattle

Cell-resolved maps provide mechanistic insight into how genetic variation shapes economically important traits, offering a valuable resource for functional studies, cell-informed precision breeding strategies, and the design of large-scale molecular phenotyping.

Bo-Yu Zhang, Shiyuan Qiu, Zhen-Wei Du et al. · 0 citations

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