AI Networking Cookbook: Practical recipes for AI-assisted network automation and development
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Variable XCI is found in CRISPR-edited female iPSCs, which was largely preserved in iPSC-derived neurons and predominantly influenced X-linked genes, which has significant implications in hiPSC-based modeling of neurodevelopmental disorders.
Human induced pluripotent stem cells (hiPSCs) provide a translational platform to interrogate the impact of genetic risk factors for various disorders on human biology. It has been a common practice to engineer premature stop codons to model predicted loss-of-function mutations using isogenic hiPSCs, yet effects of mut...
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