Characterization of Single Ribosomes and Virus Particles with Large-Diameter Perfringolysin O Nanopores
The self-assembly of the cholesterol-dependent cytolysin Perfringolysin O (PFO) into stable transmembrane nanopores composed of 46 ± 9 monomers is reported, enabling, for the first time, resistive-pulse-based characterization of intact virus particles and ribosomes with a biological nanopore.
Andela Vracar, Veneta Salyahetdinova, S. Balog et al.
· bioRxiv · 0 citations