Starship transposons mobilise via a circular intermediate with potential biotechnological applications
It is demonstrated that a synthetic circular intermediate, or “starmid”, is sufficient for recombinase-dependent integration into the host genome and that circularisation enhances expression of the starship-encoded tyrosine recombinase through juxtaposition of 3′ and 5′ terminal sequences.
Allira Baericke, Vanta J. Jameson, Andrew S. Urquhart
· bioRxiv · 0 citations