Transcriptomic profiling of human iPSC-derived Schwann-like cells reveals NF2-regulated gene regulatory networks
Abstract Schwann cells are vital to development and maintenance of the peripheral nervous system and their dysfunction has been implicated in a range of neurological and neoplastic disorders, including NF2 -related schwannomatosis ( NF2 -SWN). We have developed a novel human induced pluripotent stem cell (hiPSC) model...
Olivia Lazaro, Sihong Li, Jacob S. Smiley et al.
· Scientific Reports · 1 citation