Author

Annie Kathuria

2 papers indexed here

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Open access Oct 2026

Paracrine bone-derived senescent secretome is associated with spatially patterned extracellular matrix remodeling and altered biomechanics in human brain organoids

The results suggest that chronic paracrine exposure to senescent osteocyte-derived secretome is associated with localized extracellular matrix-related remodeling and mechanical vulnerability in human brain tissue, providing insight into how peripheral cellular senescence may contribute to regional brain fragility durin...

Chanul Kim, Luke Daniel L. Ofria, Hossein Shaygani et al. · Stem Cells · 0 citations

#diffusion models Open access Sep 2026

Transforming Brain Organoids Into Functional Platforms: Convergence of Engineering, Imaging, AI, and Ethics

ABSTRACT Brain organoids are self‐organizing 3D aggregates derived from pluripotent stem cells and thus mirror many aspects of human brain development, including gene expression programs, spatial organization, and neuron subtype specification. As a result, these organoids have been used to emulate neurodevelopmental, n...

Aishwarya Pantula, K. Joshi, Swarangi Samant et al. · Advancement of science · 0 citations