Females show less hypoxia-induced blood-brain barrier disruption in aged mice: a protective role for CD11c
Aging is associated with a decline in blood-brain barrier (BBB) integrity. Interestingly, recent reports suggest that females may be more resistant to BBB disruption than males. Using a robust model of hypoxia-induced BBB disruption, we exposed aged (20 months) male and female mice to chronic mild hypoxia (CMH; 8% O 2...