Sustainable UHPLC-MS/MS assay for ultra-sensitive simultaneous quantification of amoxicillin and flucloxacillin with application to a bioequivalence study.
The developed UHPLC-MS/MS method was successfully applied in a bioequivalence study involving 33 healthy volunteers following oral administration of a single 5 mL dose of Flucamox® 250 mg, enabling comprehensive pharmacokinetic evaluation while promoting sustainable and resource-efficient analytical practices.