Author

B. Race

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Review Sep 2026

Life at the interface: Byron Caughey’s search for prion disease inhibitors through chemistry, structure, and cell physiology

James A. Carroll, J. Soukup, B. Groveman et al. · Acta Neuropathologica · 0 citations

#protein folding Open access Sep 2026

Exposure of cells to prions induces prion strain dependent changes in mitochondrial redox state and respiration.

During initial prion infection, PrPSc drives mitochondrial dysfunction in a manner that is both strain dependent and independent of PrPC expression, while persistent prion infection increases mitochondrial sensitivity to cellular stress.

Daniel Shoup, L. Varner, B. Race et al. · Journal of Cell Science · 0 citations