B. Yaswanth Vinayak1, D. Nagamani2, K. Dinesh3, M. Mallikarjun4, P. Mallieswari5, Are Pradeepthi6*

NANOTECHNOLOGY-ENABLED NON-VIRAL DELIVERY SYSTEMS FOR CRISPR/CAS9 GENE THERAPY: CURRENT PROGRESS AND TRANSLATIONAL CHALLENGES

CRISPR/Cas9 has become a versatile platform for programmable genome editing and has generated substantial interest as a therapeutic modality for inherited and acquired diseases. However, clinical translation depends not only on editing specificity but also on safe and efficient delivery of the Cas9 nuclease and guide R...