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Basudeb Mondal

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#protein folding Open access Sep 2026

Proteolytic Activation of T Cell Engagers And Bispecific Proteins Using Modular Coiled-Coil Peptides.

Protease-responsive masked BiTEs using OKT3 and UCHT1 mAb clones are developed, that activate T cells only after exposure to tumor micro-environment-associated proteases and stimulate the T cell activation by their tumor-antigenic targets, and could be of broad utility towards helping constrain BiTE-mediated immune-act...

Basudeb Mondal, Yusef A. Haikal, Gabriel A. Kwong et al. · 0 citations

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