Second-Generation JNK Activity Reporter Illuminates the Mechanism of AT1R-Induced JNK Activation.
c-Jun N-terminal kinases (JNKs) are central integrators of cell stress and are responsible for a multitude of signaling and gene expression changes in response to various environmental cues. Here, we describe the development of JNKAR2, a second-generation FRET-based JNK biosensor. JNKAR2 exhibits a ∼3.9-fold higher res...
Daniel Stehle, Ben Li, N. Han et al.
· ACS Sensors · 0 citations