Author

Ben P. Williams

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Open access Oct 2026

DNA demethylases constrain multigenerational methylome and transcriptome divergence

In plants, animals and fungi, DNA methylation is important for the silencing of repetitive DNA and impacts the expression of a subset of genes. DNA methylation landscapes exhibit a high degree of stability over generations, yet this stability is the product of multiple dynamic methylation and demethylation pathways. Ho...

Anna Dmitrieva, Kate I. Christensen, Ben P. Williams · bioRxiv · 0 citations

#gene editing Review Open access Oct 2026

When DNA methylation integrity fails: Lessons from plant aging and tissue culture.

Plants maintain DNA methylation landscapes with high fidelity. Multiple pathways are coordinated to maintain DNA methylation patterns over many millions of cell divisions, reproductive generations and even evolutionary timescales. As DNA methylation maintenance is typically a robust and accurate process, scenarios in w...

Yin-Wei Zeng, Ken Chen, Ben P. Williams · Current opinion in plant bio... · 0 citations