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Author

Bernhard Dumoulin

3 papers indexed here

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Open access Oct 2026

A functional investigation of the natriuretic peptide receptor 3 (NPR3) in glomerular stability and disease progression

Podocytes are essential for maintaining the structural and functional integrity of the glomerular filter. While the signaling properties of the natriuretic peptide receptor 3 (NPR3) have long been debated, emerging data suggest a signaling role in podocytes through interactions with slit diaphragm (SD) proteins. Howeve...

Badr Khbouz, Bernhard Dumoulin, Maciej K. Kocylowski et al. · 0 citations
#gene editing Open access Oct 2026

Transcription factor TBX2 is a key regulator of vascular calcification.

BACKGROUND AND AIMS Vascular calcification predicts cardiovascular mortality more strongly than traditional risk factors, yet its molecular basis remains poorly understood. The burden is greatest in chronic kidney disease (CKD), where disordered mineral metabolism accelerates arterial mineral deposition. METHODS Cros...

Shen Li, Hong-Bo Liu, Su-Jin Lee et al. · 0 citations
Open access Jul 2026

Single-cell spatial mapping of human kidney development implicates the microenvironment in guiding cell fate decisions

This analysis revealed unrecognized plasticity, showing that cell fate established during early patterning can be later revised and provides a potential mechanism for how cell fate is robustly established in complex patterned tissues.

Jonathan Levinsohn, Samuel Grindel, Bernhard Dumoulin et al. · 2 citations

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