Author

Biyao Yang

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Review Open access Aug 2026

CRISPR technologies for detecting DNA and RNA methylation: Mechanisms, platforms, and translational opportunities

Abstract DNA and RNA methylation are key epigenetic and epitranscriptomic modifications involved in gene regulation, genome stability, RNA metabolism, and disease progression. Aberrant methylation patterns in cell‐free DNA and RNA have emerged as valuable biomarkers for cancer detection, disease monitoring, and therape...

Kai-Xin Chen, Bi-Yao Yang, Rui Sang et al. · Bioengineering & Translation... · 0 citations

#gene editing Aug 2026

Light- and X-ray-Activated Liposomes for Controlled Gene Editing and Drug Delivery.

This protocol presents methods for fabricating and characterising two distinct verteporfin (VP)-integrated lipid nanoparticle formulations and demonstrates knockout of up to approximately 326 slow-muscle fibres per zebrafish embryo via light activation and significant tumour growth suppression via X-ray-triggered doxor...

Yagiz A. Aksoy, Biyao Yang, G. Liew et al. · Journal of Visualized Experi... · 0 citations