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Sponsored AI Networking Cookbook: Practical recipes for AI-assisted network automation and development AI Networking Cookbook: Practical recipes for AI-assisted network automation and development

Author

Birkley Lim

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Sep 2026

Abstract B110: Effector CD4 T cells convert transient responses to KRAS targeted therapy into long-term durable remissions in pancreatic cancer

Pancreatic ductal adenocarcinoma is refractory to most therapies, including immunotherapies, where reinvigoration of CD8 T cells with immune checkpoint blockade is insufficient to induce long-term durable remissions. Direct inhibitors of KRAS are clinically promising, although acquired resistance is common. To test i...

Li Qiang, Megan T. Hoffman, Jung-Ho Chun et al. · 0 citations
Open access Jul 2026

An IL-34–IGF-1 inflammatory axis fuels KRAS-mutant lung cancer progression

It is shown that KRASG12D mutations in lung epithelium drive proliferation of resident, embryonically-derived alveolar macrophages, which then promote tumor cell proliferation and protection from ferroptosis, leading to tumor progression.

Jaroslav Zak, Hui Chen, Erpei Wang et al. · 0 citations

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