Open access
Sep 2026
The Histone Methyltransferase KMT2D promotes Natural Killer cell effector molecule release
RAB3D-deficient human NK cells reduced the release of GZMB and IFN-γ, without impacting intracellular levels, and KMT2D acts as a conserved epigenetic regulator of mature NK cell functions, promoting rapid effector molecule release.
Katelynn R. Kazane, Jeong Hyun Ji, Georgia R. Lill et al.
· bioRxiv · 0 citations