Distinct Bone Marrow Metabolic Profiles at Relapse Compared with Initial Diagnosis in Pediatric Acute Lymphoblastic Leukemia—An LC-MS Metabolomics Study
Background/Objectives: Relapse remains the leading cause of mortality in pediatric acute lymphoblastic leukemia (ALL), underscoring the need for novel biomarkers and therapies. The objective of this study is to identify distinct metabolomes associated with relapsed ALL, using bone marrow aspirated at the relapse episod...