Abstract Background 22q11.2 deletion syndrome (22q11DS) is strongly associated with aberrant neurodevelopment, including decreased cognitive functioning and schizophrenia spectrum disorders (SSDs). While the different core domains of IQ have distinct clinical ramifications, their collective profile has not been well-ch...
A. Fiksinski, Rielle Wierenga, D. McDonald-McGinn et al.· Psychological Medicine· 0 citations
Extrapyramidal symptoms (EPS) have been described as intrinsic to schizophrenia spectrum disorders (SSD), beyond medication-induced effects. Among EPS, parkinsonism is the most prevalent subtype and has been linked to poorer clinical and functional outcomes. We aimed to examine the relationships between parkinsonism an...
Joaquin Galvañ, J. Lopez-Morinigo, Gonzalo Salazar de Pablo et al.· Schizophrenia Research· 0 citations
SIB in CHR-P individuals reflects a multidimensional clinical profile primarily outside of core psychosis-risk symptoms, and overall subthreshold psychotic symptoms across the SIB spectrum indicate increasing overall subthreshold psychotic symptoms across the SIB spectrum.
S. Damiani, M. Orlandi, U. Provenzani et al.· Acta Psychiatrica Scandinavi...· 0 citations
These findings demonstrate that aberrant cortical folding in schizophrenia is constrained by network topology and molecular architecture, and establishes sulcal morphology as a mechanistically grounded biomarker that may help differentiate the neurodevelopmental trajectories of psychiatric disorders.
J. González-Peñas, H. Schnack, Carmen Rueda Hernández et al.· Biological Psychiatry· 0 citations
A relationship between sleep disturbance and suicidal ideation/attempts in CHR is supported, with participants who had lifetime ideation and attempts experiencing more sleep disturbance than those with no ideation or attempts.
H. Wastler, Aubrey M. Moe, Alexandra M Blouin et al.· Schizophrenia Bulletin Open· 0 citations
Prolonged CAL is linked to higher risk of FEP, preferentially affective psychosis in females, poorer functioning, and developmental potentiation of polygenic liability.
Á. Andreu-Bernabeu, J. González-Peñas, M. Bernardo et al.· Schizophrenia bulletin· 0 citations
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