Oleuropein regulates neuronal survival and Histone acetylation in Parkinson’s disease: cellular and epigenetic insights
The data suggest that OLE regulates at both cellular and epigenomic levels by promoting the enrichment of acetylated H3K9 on the neuro-survival gene promoter region in the nigrostriatal region of PD mice, suggesting its neuroprotective role might involve in modulating chromatin structure and epigenetic regulation in PD...