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Author

C. D. de Andrea

3 papers indexed here

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Open access Oct 2026

RNA and protein are not interchangeable in single-cell spatial multi-omics

Spatial transcriptomics is increasingly used to infer cellular phenotypes, molecular interactions, and functional tissue organization from RNA, although most of these biological processes are ultimately mediated by proteins. Here, we directly tested the interchangeability of spatial RNA and protein measurements using p...

Sergi Cervilla, D. Grases, Noelia Montesdeoca et al. · 0 citations
Aug 2026

Antibody-Drug Conjugates Synergize with Agonist Anti-CD137 Monoclonal Antibodies in Solid Tumors.

Antibody-drug conjugates (ADCs) show clinical efficacy against several solid malignancies, inducing cytotoxic effects in malignant cells accompanied by changes in the composition of the tumor stroma. The therapeutic effects of some ADCs have been shown to be potentiated by combination with anti-PD(L)1 checkpoint inhibi...

Gabriel Gomis, Claudia Herrero, Saioa Arrieta-Aranzueque et al. · 1 citation
Open access Sep 2026

TNFR1 expression on cancer cells mediates immune escape and an immunosuppressive microenvironment

Evidence is provided for a key role of TNFR1, as expressed by malignant cells, in orchestrating a pro-tumor immunosuppressive environment through secondary inflammatory mediators through secondary inflammatory mediators.

Elixabet Bolaños, Lorena Cañas-Zabala, Irene Olivera et al. · 0 citations

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