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Sponsored AI Networking Cookbook: Practical recipes for AI-assisted network automation and development AI Networking Cookbook: Practical recipes for AI-assisted network automation and development

Author

Caroline Graff

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Open access Aug 2026

Data-driven mapping of known and novel fluid biomarker progression profiles in genetic frontotemporal lobar degeneration

The model’s accurate estimation of disease stages underscores the value of DEBM for patient stratification, offer a promising tool to support clinical trial design and provide a temporal ordering of multiple CSF proteins.

J. D. De Houwer, Wenjie Kang, Renee van Buuren et al. · 0 citations
Open access Sep 2026

Protein Biomarkers in Risk and Prognosis of Amyotrophic Lateral Sclerosis

Plasma and cerebrospinal fluid (CSF) protein biomarkers in amyotrophic lateral sclerosis (ALS) may provide insight into disease mechanisms and yield clinically useful biomarkers.

Lu Pan, C. Hou, Christina Seitz et al. · 0 citations
Open access Jul 2026

Machine-learning MRI stratification of genetic frontotemporal dementia for clinical trial enrichment

Machine-learning stratification of genetic FTD reveals a progressive and a dissociated disease track and provides individualized progression scores that closely track clinical status, enabling smaller, more efficient prevention and early-intervention trials than conventional MRI or NfL markers alone.

M. Soltaninejad, Y. Iturria-Medina, A. Bouzigues et al. · 0 citations
Open access Aug 2026

Educational attainment and sex modulate clinical outcomes in genetic frontotemporal dementia

Sex and educational attainment significantly affect the development and maintenance of cognitive reserve in individuals with genetic FTD, and underscore the importance of identifying disease-modifying interventions since the presymptomatic stages of the disease.

E. Premi, Damiano Archetti, A. Redolfi et al. · 0 citations
#protein folding Open access Aug 2026

Cerebrospinal fluid YWHAG:NPTX2 ratio predicts clinical severity and future phenoconversion in frontotemporal lobar degeneration

Frontotemporal lobar degeneration (FTLD) is a common cause of early-onset dementias marked by progressive declines in behavior, cognition, and/or movement. FTLD neuropathologies, including TDP-43 proteinopathies and primary tauopathies, do not have reliable fluid biomarkers for in-vivo diagnosis nor biomarkers that dir...

H. Oh, J. Downer, Connor D. Dietz et al. · 0 citations
Open access Jul 2026

Clinical genome sequencing in neurodegenerative diseases-outcome in the first 500 patients.

In FTD and ALS, these results support universal access to genetic testing independent of age at onset or family history, and provide a clear diagnostic advantage in NDDs marked by substantial clinical and genetic overlap.

Emma Ehn, H. Thonberg, Inger Nennesmo et al. · 0 citations

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