Pathogenic KIF1A variants differentially disrupt axonal trafficking and impede synaptic development
The nervous system relies on billions of neurons connected through trillions of synapses to support vital functions. Despite the importance of this synaptic network, cellular mechanisms dictating synapse formation during human neurodevelopment remain unclear. Long-distance trafficking by the microtubule motor KIF1A is...
Jayne Aiken, Carris Borland, Nicolas Marotta et al.
· Journal of Cell Biology · 0 citations