Author

Chandra Sourav

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Open access Jul 2026

Immunoinformatics-Guided Design and In Silico Evaluation of a Multi-Epitope Vaccine Against Influenza A H10N5 and H3N2 Strains Based on Hemagglutinin and Neuraminidase Proteins

The immunoinformatics based vaccine design and multi-layered computational validation of a 419-amino-acid multi-epitope subunit vaccine construct targeting conserved hemagglutinin (HA) and neuraminidase (NA) antigens identified through multiple sequence alignment of the avian H10N5 human reference strain sequences are...

Muhammad Zeeshan Shabbir, Prem Kumar, Muhammad Atiq ur Rehman et al. · bioRxiv · 0 citations

Jul 2026

Directed Mutagenesis of Catalytic Residues in L-Asparaginase II from Salmonella paratyphi: Structural, Functional and Stability Analysis Using In-Vitro, Docking and Simulation Studies.

Findings demonstrate that rational site-directed mutagenesis can effectively enhance both the catalytic efficiency and thermal stability of recSalA and indicate that the introduced mutations preserve the overall protein architecture.

Ejlal Mohamed Abdullah, Mohd Shahnawaz Khan, F. S. Ataya et al. · Applied Biochemistry and Bio... · 0 citations