Open access
Jul 2026
Meta-analyses of the NEPTUNE dataset related to high and low risk FSGS and cellular APOL1 models identifies Calcium signalling, mTOR signaling and inflammation-associated pathways as operative in APOL1-mediated kidney disease
A signature of up- and down-regulated genes between biopsies from FSGS patients with APOL1 HR and LR kidney biopsies could be assigned as associated with Calcium and mTOR signaling and down-regulated immune response.
Wasco Wruck, Chantelle Thimm, Tama Amin et al.
· bioRxiv · 0 citations