Whole tumor cell vaccines are uniquely positioned for personalized immunotherapy by presenting the full repertoire of tumor-associated antigens to counter tumor heterogeneity, yet their translation is persistently hindered by poor immunogenicity and the requirement for multiple administrations. Herein, we introduce a s...
Hong-Ze Ren, Qing-Ying Wu, Wei Yang et al.· Angewandte Chemie· 0 citations
Conjugated polymer‐based phototheranostics have attracted considerable attention for cancer treatment owing to their excellent photothermal properties and biocompatibility. However, integrating efficient photodynamic activity into conjugated polymer systems without compromising their intrinsic photothermal performanc...
Xiang-Mei Wen, Meng Chen, Xue-Yan Yao et al.· Advanced Functional Material...· 0 citations
A living bacterial hybrid reactor is developed by integrating Shewanella oneidensis MR-1 with Cu(II)-based zeolitic imidazolate frameworks to enable metabolism-guided and tumor-confined bioorthogonal catalysis, overcoming key limitations of conventional bioorthogonal catalysis and enabling precise, tumor-confined thera...