Aug 2026
SREBF2 promotes mitophagy and protects against ferroptosis via Cav-1-regulated PINK1/Parkin signaling in ischemic heart failure
Results demonstrate that SREBF2 mitigates MI-induced HF by activating the Cav-1/PINK1/Parkin axis to promote mitophagy and inhibit ferroptosis, and identify SREBF2 as a promising therapeutic target in heart failure.
Jia Li, Jia Liu, Fan-Yan Luo et al.
· Journal of molecular medicin... · 0 citations