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Author

Cheng-Xia Kan

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Review Aug 2026

The Mediating Role of Atherogenic Index of Plasma in the Association Between Dietary Inflammatory Index and Metabolic Syndrome: Evidence from NHANES and CHARLS

Aims: Metabolic syndrome (MetS) is a growing public health burden driven by chronic low-grade inflammation and lipid metabolic dysregulation, with diet as a major modifiable determinant. Proinflammatory diets [assessed by the dietary inflammatory index (DII)] are linked to MetS risk, but the underlying metabolic pathwa...

Jiajun Sang, Ke-Xin Zhang, Cheng-Xia Kan et al. · 0 citations
Review Aug 2026

Homeobox genes in endocrine tumorigenesis: mechanisms, tumor microenvironment interaction, and therapeutic potential

A deeper mechanistic understanding of HOX-driven networks will aid the development of innovative biomarkers and therapies, thereby advancing precision medicine in endocrine oncology, and advancing precision medicine in endocrine oncology.

Si-Lin Kong, Ke-Xin Zhang, Cheng-Xia Kan et al. · 0 citations
Review Aug 2026

Programmed cell death in kidney disease: integrated crosstalk among ferroptosis, pyroptosis, apoptosis, and cuproptosis

A “metabolic crisis-cascade” framework is proposed, in which progressive disruption of energy metabolism, redox balance, and metal homeostasis acts as a unifying upstream mechanism linking multiple PCD pathways during kidney injury and preventing AKI-to-CKD transition.

Jiajun Sang, Zhen-Tao Guo, Cheng-Xia Kan et al. · 0 citations
Jul 2026

Rising Global Burden and Sex Disparities in Nonmelanoma Skin Cancer: 1990-2021 Trends With Projections to 2036.

The global burden of NMSC is rising, and men consistently experience higher incidence, mortality, and DALY rates than women, and the expanding sex gap highlights the urgent need for targeted and sex-specific prevention, early detection, and public health interventions.

Wenqiang Zhang, Ke-Xin Zhang, Cheng-Xia Kan et al. · 0 citations

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