Author

Cheng Yang

2 papers indexed here

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Open access Aug 2026

Formononetin ameliorates bleomycin-induced pulmonary fibrosis in mice via targeting USP5

Background Idiopathic pulmonary fibrosis (IPF) is a chronic and progressive interstitial lung disease with limited therapeutic options. Transforming growth factor beta 1 (TGF-β1) is a major profibrotic mediator that promotes fibroblast activation and extracellular matrix (ECM) deposition. This study aimed to evaluate t...

Yong-Ping Wang, Xue-Ze Liu, Hao Song et al. · Journal of Thoracic Disease · 0 citations

#protein folding Open access Sep 2026

Pirfenidone Lung Distribution Amplified in Idiopathic Pulmonary Fibrosis: Roles of tight junction disruption and drug transporter dysregulation.

It is suggested that IPF pathogenesis creates a permissive microenvironment for PFD through simultaneous enhancement of paracellular permeability and active cellular uptake through simultaneous enhancement of paracellular permeability and active cellular uptake.

Xiao-Ting Gu, Chao-Yue Zheng, Bo Li et al. · European Journal of Pharmace... · 0 citations