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Author

Chloe Kan

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Aug 2026

Distinct amyloid-β filament fold in individuals with APP Flemish mutation

Cryo-electron microscopy structures of amyloid filaments extracted from the postmortem parietal lobes of two individuals representing the only two known Flemish pedigrees worldwide provide insight into the molecular basis of Flemish-type dementia and cerebral hemorrhage.

Peerzada Shariq Shaheen Khaki, P. A. Guillen-Poza, Carlton Wong et al. · 0 citations
Review Open access Aug 2026

Harnessing macrophage signaling pathways and scalable engineering for next-generation immunotherapies

Leveraging concepts of macrophage tissue plasticity highlights the potential of macrophages as next-generation cell therapeutics with broad potential in oncology and beyond, bridging fundamental immunology with translational medicine.

Daniela Paasch, Kathrin Haake, Chloe Kan et al. · 0 citations

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