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Christoforos Nikolaou

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#protein folding Open access Sep 2026

Evolutionary origins of protein novelty across an entire yeast subphylum

A broad computational investigation of genetic and protein novelty throughout the entire subphylum of Saccharomycotina yeasts shows that “invention” of new folds occurs more frequently through de novo emergence, and illustrates cases of evolutionary “re-invention” of existing protein folds from noncoding sequences.

Emilios Tassios, Nikolaos Pirgelis, D. Rinker et al. · 0 citations

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