Author

Christopher S. Godbehere

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Open access Jul 2026

3D nanoscale reconstruction of human airway multiciliogenesis reveals cellular architecture remodeling and cilia-mitochondria link via rootlets.

This work uncovers a structural and functional association between motile cilia and mitochondria mediated by rootlets, striated cytoskeletal fibers that remain poorly characterized in human airway multiciliated cells.

Aaran Vijayakumaran, Christopher S. Godbehere, Analle Abuammar et al. · Cell Reports · 1 citation

#gene editing Open access Aug 2026

Gene editing of alveolar organoids reveals AT2 dysfunction due to endosomal SFTPC accumulation.

Endosomal dysfunction and polarity loss are established as drivers of SFTPC-I73T-mediated epithelial injury and mechanisms that may underlie AT2 dysfunction in disease more broadly are highlighted.

Eimear N. Rutherford, Dawei Sun, Kyungtae Lim et al. · American Journal of Respirat... · 0 citations