Transcriptomic identification of mitophagy-related plaque markers HAND2, NRP1 and RNF213, with external replication and in vivo validation of MLXIP
Atherosclerosis is a leading cause of cardiovascular mortality, and mitophagy dysfunction contributes to its pathogenesis. However, the mitophagy-related molecular signatures that could serve as plaque-associated markers remain incompletely characterized. Paired differential expression analysis of GSE43292...