Author

D. Dell’Orco

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Review Open access Aug 2026

Tracking Neural, Sensory, and Sensorimotor Adaptation to Progressive Vision Loss in Inherited Retinal Dystrophies: A Multimodal Longitudinal Study Protocol

Individuals with inherited retinal dystrophies (IRDs) undergo a slow, genetically heterogeneous loss of vision, yet how the visual cortex and non-visual sensory, motor, and psychological systems adapt to this deprivation remains poorly characterized. Existing evidence comes mainly from single-modality, cross-sectional...

A. Verroca, E. Franchin, S. Mele et al. · medRxiv · 0 citations

#protein folding Open access Sep 2026

Understanding the strengths and limitations of recombinant protein studies

Recombinant proteins are the workhorse of modern biochemical research, yet their use in vitro is routinely questioned on grounds of physiological relevance. Here we provide a structured guide to the strengths and limitations of recombinant protein studies, framed within the broader contrast between systemic (top-do...

D. Dell'Orco, Karl-W Koch · Frontiers in Molecular Biosc... · 0 citations

Open access Aug 2026

Residual cortical responses and network reorganization in inherited retinal degeneration: electrophysiological evidence

Retinitis pigmentosa (RP) progressively deprives the retina of input, but whether the responsiveness of the visual cortex declines in parallel, remains preserved, or increases through compensatory gain remains unclear. Indeed, a weaker visually evoked response cannot, on its own, distinguish these possibilities, since...

I. Siviero, A. Verroca, S. Mele et al. · bioRxiv · 0 citations