COQ4 and COQ8A Primary Deficiencies: A Review of Proposed Therapeutic Strategies
In this article we have reviewed potential therapeutic strategies relating to two of the primary coenzyme Q10 (CoQ10) deficiencies, COQ4 and COQ8A; these disorders have been grouped together because of their complimentary roles in stabilising the CoQ10 enzyme complex, Complex Q, as well as the difficulty in treating ei...