Mitochondrial Metabolic Reprogramming and Immune Evasion in Colorectal Cancer: Research Advances and Mechanistic Perspectives
Colorectal cancer (CRC) is one of the most prevalent malignancies of the gastrointestinal tract worldwide. Notably, most patients with microsatellite-stable (MSS) tumors show primary resistance to immune checkpoint inhibitors (ICIs), creating an unmet clinical need. The mechanisms underlying immune evasion and strategi...