PURPOSE
Examining circadian hypothalamic-pituitary-adrenal (HPA) axis activity during adolescence is vital for understanding physiological changes. Limited research explores risk and protective factors for diurnal HPA activity. This study investigates how adverse childhood experiences (ACEs) and coping are associated with changes in diurnal cortisol patterns, using a combination of physiological biomarkers (i.e., salivary cortisol), daily diaries, and longitudinal assessments spanning two years.
METHODS
The sample included 316 Chinese adolescents (33% females; T1 Mage = 10.79 years, SD = 0.84). At T1, adolescents reported ACEs, completed 7-day diaries on coping, and provided saliva samples for three consecutive days. Two years later (T2), adolescents completed a follow-up assessment on diurnal cortisol activity. Latent change score modeling was conducted to investigate changing patterns in diurnal cortisol and associations of ACEs and coping with the changing patterns.
RESULTS
From T1 to T2, waking cortisol decreased, CAR increased, and diurnal cortisol slopes became steeper. ACEs were associated with initial levels of diurnal cortisol activity but not changes in it: more ACEs were linked to higher T1 waking cortisol and a smaller T1 CAR. Higher ACEs were also associated with later wake-up times; later wake-up was associated with lower T1 CAR, more blunted T1 diurnal slopes, and flatter diurnal slopes across time. Daily coping (mean and variability) moderated the associations between ACEs and diurnal cortisol.
CONCLUSION
By observing coping as a moderator between ACEs and cortisol patterns, this study demonstrates that associations between ACEs and diurnal cortisol differ across adolescents' coping use and coping variability.
Mingjun Xie, Yijia Li, Yueqing Hu et al.· Psychoneuroendocrinology· 0 citations
This study sought to examine whether diurnal cortisol served as an intermediary pathway linking childhood adversity and daily hassles to adolescent sleep behaviors (i.e., duration and quality). Data were drawn from 255 Chinese adolescents (32.2% female; Mage = 11.678 years, SD = 0.741, range = 10-14 years). Adolescents filled out a survey on demographics and childhood adversity at T1. One year later (T2), they completed 7-day reports on daily hassles and sleep behaviors and provided saliva samples for 3 consecutive days. Six months later (T3), adolescents completed a follow-up survey on their sleep behaviors. Multilevel structural equation models were conducted to examine the mediating effects of diurnal cortisol on associations between stressors and sleep duration and quality. Specific associations emerged between stressors and adolescent diurnal cortisol: Adolescents who reported greater childhood adversity at T1 exhibited a smaller cortisol awakening response (CAR) at T2; by contrast, on days when adolescents perceived more daily hassles, they exhibited a larger CAR the next day. For links between diurnal cortisol and sleep behaviors, distinct associations were observed for daily (within-person) versus longer term (between-person) effects. Finally, waking cortisol and CAR mediated the links between prior-day daily hassles and next-day sleep duration; the indirect effects of diurnal cortisol were not supported for the links between childhood adversity and sleep behaviors. Observing the temporal, time-lagged mechanism of diurnal cortisol explaining the links between daily stressors and sleep behaviors, this study points to important implications for practices on promoting adolescent sleep health. (PsycInfo Database Record (c) 2026 APA, all rights reserved).
Mingjun Xie, Qianqian Gao, Wei Wang et al.· Developmental Psychology· 0 citations