Aug 2026
Analytical validation of a modified wild-type blocker qpcr assay for the sensitive DNA-based detection of NPM1 type A in acute myeloid leukemia
The modified WTB-qPCR assay offers a rapid, highly sensitive, and cost-effective DNA-based method for MRD monitoring in NPM1-A–mutated AML, and its strong analytical performance and straightforward workflow support its implementation as a routine diagnostic tool in clinical laboratories.
Pejman Hamedi-Asl, Dariush Hamedi-Asl, Shaharbano Rostami et al.
· Molecular Biology Reports · 0 citations