Joint steering of protein generation across multiple target properties
Ideally, protein design could optimize several properties at once while ensuring the protein satisfies basic biophysical constraints such as folding, stability, solubility, and expression. However, most guided generation methods optimize only one or two simple objectives. We developed a workflow that uses predictive mo...
Prachee Avasthi, Josie Bircher, James Aaron Kraemer et al.
· Arcadia Science · 0 citations