Author

Diane S. Krause

2 papers indexed here

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Review Open access Sep 2026

RBM15 in leukemogenesis: an emerging regulator at the interface of RNA biology and hematopoiesis

This review summarizes RBM15 structure, function, and regulation, and highlights its emerging roles in leukemia, including AMKL and myelodysplastic syndromes, while outlining key questions for future studies.

Jether Amos Espinosa, Madeline Y. Mayday, Abigail R. Robb et al. · Trends in Cancer · 0 citations

#gene editing Open access Sep 2026

Reverse genetics in humanized mice reveals CARD8-mediated pyroptosis causing pancytopenia in human DPP9 deficiency

The results reveal a unique human mechanism of disease and offer therapeutic insight for this inflammasomopathy and CRISPR editing of human CD34+ hematopoietic stem and progenitor cells (HSPCs) led to very efficient and persistent gene deletion in vivo.

Tian-Li Xiao, J. R. Brewer, Maximillian J. Carlino et al. · Journal of Clinical Investig... · 0 citations