Open access
Sep 2026
Induced degradation of Ufd1 reveals regulation of cohesin by the VCP/p97Ufd1-Npl4 complex
The p97-Ufd1-Npl4 complex targets ubiquitylated RAD21 to extract a subpopulation of cohesion specifically in S-phase to facilitate DNA replication and suppress replication-associated DNA damage.
Daniella Munro, M. Reinders, Aikaterini Pravi et al.
· Life Science Alliance · 0 citations