Author

Dominique A. Baldwin

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Open access Oct 2026

Overexpression of endoplasmic reticulum acetyl-CoA transporter AT-1 alters neuronal metabolism, growth, and synaptic activity

Summary Acetyl-CoA is a molecule central to cellular metabolic homeostasis. As part of the secretory pathway, acetyl-CoA is imported into the endoplasmic reticulum (ER) by a membrane-bound transporter AT-1 (SLC33A1). AT-1 mutations have been linked to peripheral neuropathy, developmental delay with premature death, and...

Eric R. McGregor, C. McGill, N. Arp et al. · iScience · 0 citations

RISING STAR ABSTRACTS Beyond Ensemble Measurements: Resolving Antigen Binding and Conformational Heterogeneity in Multispecific Antibodies

These findings reveal that the RSV F antigen recognizes both the wild-type and AAS-mutated bispecific antibodies in a conformation-dependent manner, with binding preferentially observed for larger conformations.

Fanny C. Liu, Thais Pedrete, Andrew H. Beaven et al. · 0 citations