Author

Dong-Lin Yang

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Open access Oct 2026

Independent association of the CHG index with cardiometabolic multimorbidity: real-world evidence from community and clinical datasets

Cardiometabolic multimorbidity (CMM) is an increasing public health challenge in aging populations. The cholesterol–high-density lipoprotein–glucose (CHG) index is an emerging metabolic marker, but its association with prevalent CMM has not been sufficiently evaluated across community and hospitalized populations....

Ze-Xu Cui, Tian-Hao Lan, Min-Chin Lu et al. · Frontiers in Public Health · 0 citations

Aug 2026

Integrin αVβ3-mediated focal adhesion signaling promotes fibroblast activation during renal fibrosis.

Renal fibrosis is a progressive pathological process underlying chronic kidney disease (CKD), characterized by persistent fibroblast activation and excessive extracellular matrix accumulation. Although integrin-dependent focal adhesion signaling has been implicated in tissue fibrosis, its role in renal fibroblast activ...

Dongdong Wu, Jing Zhao, Xinrui Chang et al. · Biochemical Pharmacology · 0 citations

Review Jul 2026

Cellular Senescence in Diabetic Cardiomyopathy: Mechanistic Insights and Therapeutic Perspectives.

This review integrates current insights into the complex interplay among metabolic stress, mitochondrial injury, and cellular senescence in Diabetic cardiomyopathy and highlights promising directions for mechanism-based interventions aimed at combating diabetic cardiac remodeling.

Ting Ye, Dong-Lin Yang, Xinrui Chang et al. · Cardiovascular Drugs and The... · 0 citations