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Author

Donglu Shi

3 papers indexed here

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Review Open access Sep 2026

Breaking Biological Barriers: Engineering Nanocarriers for Efficient Drug and Gene Delivery through Nano-Bio Interfaces and Biophysical Design

A persistent challenge in nanomedicine is achieving functional delivery of therapeutic molecules across physiological barriers. Organs impose distinct transport constraints, including the blood–brain barrier, renal filtration, hepatic sequestration, and pulmonary clearance. Although substantial effort has focused on en...

Zicheng Deng, A. Dunn, Daniel Q. Sun et al. · 0 citations
#protein folding Open access Sep 2026

Multi-Parameter Genomic Evolution of SARS-CoV-2 Across Ten US States During the Vaccination Era, 2020–2025

SARS-CoV-2 has adapted continuously since 2019, yet no multi-parameter framework has characterized this trajectory across geographically distinct United States populations. We present a systematic 13-parameter analysis of 137,059 high-quality genomes from ten diverse US states across three phases: pre-vaccination (Janu...

Som V. Thomas, Jing Chen, D. Qian et al. · 0 citations
Review Open access Sep 2026

Precision nanomedicine for pulmonary diseases: from molecular targeting to clinical translation

The pulmonary system is a vital interface between the body and the external environment, making it highly vulnerable to environmental, infectious, and genetic insults. Precision nanomedicine offers a promising strategy to overcome the limitations of conventional gene and drug therapies, including safety concerns associ...

Zicheng Deng, Wen Gao, Jonathan Do et al. · 0 citations

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