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Dongxu Li

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Open access Sep 2026

LLM-H2G: biomedical semantic-enhanced hypergraph contrastive learning for herb–disease association prediction

Herb–disease association prediction is central to computational traditional medicine, but existing graph and hypergraph methods mainly rely on observed topology and underuse biomedical textual semantics, especially in heterogeneous or sparse association networks. We propose LLM-H2G, a biomedical semantic...

Jun Zhang, Hengchuang Yin, Chao Wu et al. · 0 citations
Open access Sep 2026

Evaluating Large‐Language Models in Bioinformatics Applications

Large language models (LLMs) have significantly revolutionized natural language processing through their strong capabilities in text generation and reasoning. Yet, their applicability to bioinformatics applications remains largely unexplored. Here, we systematically evaluate state‐of‐the‐art LLMs across six represent...

Hengchuang Yin, Zi-Wen Cui, Dong-Xu Li et al. · 0 citations
Book Open access Aug 2026

Reinforced Structural Reasoning for Receptive Field Optimization in GNN toward Interpretable Graph Clustering

RGIGC formulates receptive field configuration as a structural reasoning problem and employs reinforcement learning with two Q-learning agents to infer and optimize the structural receptive field of each node to enhance the interpretability of the resulting clusters.

Yue Yang, Dongxu Li, Hengchuang Yin et al. · 0 citations

DRHIN: An Integrated and Interactive Web Server for Drug Repositioning

The DRHIN platform provides a code-free portal supporting three key predictive tasks: discovering drug-disease associations, repurposing existing drugs for new indications, and identifying potential therapies for specific diseases, making analyses accessible and reproducible.

Bowei Zhao, Dongxu Li, Yue Yang et al. · 10 citations · ⚡1
Book Open access Aug 2026

Reinforced Structural Reasoning for Receptive Field Optimization in GNN toward Interpretable Graph Clustering

Graph clustering aims to group nodes into meaningful clusters, a crucial task for understanding the behavior of complex networks and their underlying structural organization. Leveraging the expressive power of deep learning, graph neural networks (GNNs) have emerged as popular tools for performing graph clustering with...

Yue Yang, Dongxu Li, Hengchuang Yin et al. · 0 citations

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