Author

E. Afzal

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Open access Oct 2026

Association of Screen Time Exposure with Developmental Delay in Communication and Problem-Solving Skills among Children Under 5 Years of Age Presenting at Children's Hospital: An Analytical Cross-Sectional Study

Excessive screen exposure in early childhood has been increasingly associated with adverse neurodevelopmental outcomes. Objectives: To determine the association of screen time exposure with developmental delay in communication and problem-solving skills among children under five years of age presenting at a tertiary ca...

Gull Hassan, Erum Afzal, Ghulam Abbas et al. · Pakistan journal of health s... · 0 citations

#protein folding Open access Oct 2026

CNPY3 variants associated with a recessive developmental and epileptic encephalopathy affect inflammasome and TLR function

The authors' findings reveal separable effects on TLR trafficking, downstream signalling and inflammasome activation, identifying CNPY3 as a key regulator of multiple cellular pathways involved in inflammatory responses and neurodevelopment.

Vera Garloff, M. Grimmel, R. Maroofian et al. · EBioMedicine · 0 citations

Open access Sep 2026

Loss of RUBCN causes autophagy overdrive in a neurodevelopmental disorder with age-dependent neurodegeneration

The RUBCN-related disorders are established and expand as a clinically and molecularly distinct subset of autophagy-related diseases and enhances understanding of autophagy-related neurodevelopmental disorders and provides a foundation for future therapeutic investigations.

S. Efthymiou, K. Tabata, H. Dafsari et al. · medRxiv · 0 citations