Aug 2026
Loss of calbindin and rise in pT217-tau in aging monkey prefrontal cortical dendrites
Isabella Perone, D. Bolat, Zhiling Gu et al.
· bioRxiv · 0 citations
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Open access
Aug 2026
Overcoming the blood-brain barrier using central nervous system-accessing lipid nanoparticles for enhanced mRNA therapeutics.
This work designed, synthesized, and tested a series of ionizable lipids and formulated them into CNS-accessing lipid nanoparticles (CA LNPs) to deliver mRNA, and the lead candidate, CA2d LNP, demonstrated efficient mRNA delivery across the blood-brain barrier following intravenous injection.
Si-Yu Wang, Yi-Chen Zhong, Chang Wang et al.
· Proceedings of the National... · 0 citations
Review
Aug 2026
Comparative insights into insula structure and function
This work systematically evaluates current knowledge regarding homologies in the insula among model species and humans to propose research directions aimed at strengthening translational insula research and enhancing the understanding of cross-species similarities and differences.
Joey A. Charbonneau, Sarah B. Carp, Jeffrey L. Bennett et al.
· Nature Neuroscience · 0 citations