Aug 2026· Nature Neuroscience· Vol 29, pp. 2081 - 2102· 0 citations· 329 references
Medicine
TL;DR
This work systematically evaluates current knowledge regarding homologies in the insula among model species and humans to propose research directions aimed at strengthening translational insula research and enhancing the understanding of cross-species similarities and differences.
An elaborated model of the function of the claustrum in cognition is provided to explain human functional connectivity data and the discovery of a well-developed organization of the monkey claustrum into overlapping functional sub-domains provides deep insight into claustrum function when considering rodent synaptic co...
Andreas B. Wulff, Brian N. Mathur· National Science Review· 0 citations
The habenula is a small epithalamic structure that animal models have characterized as a key node linking value-laden information to midbrain monoaminergic systems. Its involvement in mood disorders has driven growing interest in characterizing its function in humans, yet the healthy baseline of habenula function from...
A. S. López, F. M. Osuna, Trevor Steward et al.· Neuroscience and Biobehavior...· 0 citations
Using high-resolution qMRI, motor cortex subdivisions controlling the leg, hand, and face in humans and chimpanzees are compared and consistently higher myelin and iron content in the hand-knob in both species are found, suggesting an evolutionarily conserved role.
M. Chauvel, E. Kirilina, I. Lipp et al.· bioRxiv· 0 citations
A first systematic review of functional neuroimaging studies reporting LS activation in humans highlights the LS as an underexplored but potentially critical structure for human socio-emotional and motivational processes, with clinical relevance for psychiatric conditions.
Julie Klinke, Kaiwen Zhang, Nicole Li et al.· Social Cognitive and Affecti...· 0 citations
The anatomical connections of the NAc with the underexplored brainstem and cerebellar connections are investigated, demonstrating overlapping connections in both species, particularly with the raphe, parabrachial, ventral tegmental area and pontis oralis.
A timely and comprehensive view of the anterior cingulate cortex’s role in adaptive and pathological anxiety is provided and an integrative model in which ACC effects depend on subregion, projection target, and behavioral context is proposed.
Emily Dew, Alexis Jones, S. Saggu et al.· Frontiers in Psychiatry· 0 citations
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