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Author

E. Papalanis

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2 papers indexed here

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Open access Jul 2026

Peptide Nucleic Acid Probes for Pretargeted Affibody-Mediated Delivery of Cytotoxic Payloads to HER2-Positive Carcinoma

These findings highlight how rational design can optimize in vivo pharmacokinetics while preserving binding properties essential for effective pretargeting, providing a foundation for developing novel targeted cytotoxic delivery systems with potentially improved therapeutic indexes.

Jacob Clinton, K. Westerlund, Astrid Haraldsson et al. · 0 citations
#protein folding Sep 2026

Targeted RPT of CEACAM5-Expressing Human Xenografts Using an Albumin-Binding Domain-Fused C9 Affibody: Proof-of-Principle Study.

ABD035-C9-C9-DOTA is a promising candidate for the development of targeted RPT of CEACAM5-expressing tumors and a significant increase in the survival of tumor-bearing mice and mild, transient toxicity is demonstrated.

Ruo-Nan Li, E. Papalanis, M. Oroujeni et al. · 0 citations

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